Target Interacting Protein Information

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Target General Information
Target Interacting Proteins
References
Target General Information  Top
Target ID T65864 Target Info
Target Name Stress-activated protein kinase 2a (p38 alpha)
Synonyms SAPK2A; P38 mitogen activatedprotein kinase; P38 Mitogen-activatedprotein kinase alpha; Mitogen-activated protein kinase p38 alpha; Mitogen-activated protein kinase 14; MXI2; MAX-interacting protein 2; MAPK 14; MAP kinase p38alpha; MAP kinase p38 alpha; MAP kinase MXI2; MAP kinase 14; Cytokine suppressive anti-inflammatory drug-binding protein; Cytokine suppressive anti-inflammatory drug binding protein; CSPB1; CSBP2; CSBP1; CSBP; CSAID-binding protein; CSAID binding protein; CRK1
Target Type Clinical trial Target
Gene Name MAPK14
Biochemical Class Kinase
UniProt ID
MK14_HUMAN 
Target Interacting Proteins  Top
Acyltransferases [+] 2 Acyltransferases +
Interacting Protein Name Cyclic AMP-dependent transcription factor ATF-2 (ATF2) Interacting Protein Interacting Protein Info
UniProt ID
ATF2_HUMAN 
Synonyms CRE.BP1; CREB.2; CREB2; HB16; TREB7
Evidence Score (E-score) 20 Experimental Evidences +
1 Biochemical Activity [1]
2 Biochemical Activity [2]
3 Biochemical Activity [3]
4 Biochemical Activity [4]
5 Biochemical Activity [5]
6 Biochemical Activity [6]
7 Biochemical Activity [7]
8 Biochemical Activity [8]
9 Biochemical Activity [9]
10 Biochemical Activity [10]
11 Biochemical Activity [11]
12 Biochemical Activity [12]
13 Biochemical Activity [13]
14 Biochemical Activity [14]
15 Biochemical Activity [15]
16 Biochemical Activity [16]
17 Biochemical Activity [17]
18 Biochemical Activity [18]
19 Biochemical Activity [19]
20 Biochemical Activity [20]
Interacting Target Name Histone acetyltransferase p300 (EP300) Clinical trial Target Interacting Protein Info
UniProt ID
EP300_HUMAN 
Synonyms Protein propionyltransferase p300; p300 HAT; P300; Histone crotonyltransferase p300; Histone butyryltransferase p300; E1A-associated protein p300; E1Aassociated protein p300
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [21]
2 Biochemical Activity [3]
Adapter proteins [+] 1 Adapter proteins +
Interacting Target Name Sequestosome-1 p62 (SQSTM1) Literature-reported Target Interacting Protein Info
UniProt ID
SQSTM_HUMAN 
Synonyms Ubiquitin-binding protein p62; Sequestosome-1; Phosphotyrosine-independent ligand for the Lck SH2 domain of 62kDa; Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa; OSIL; ORCA; EBIAP; EBI3-associated protein of 60 kDa
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [11]
2 Reconstituted Complex [22]
Ester hydrolases [+] 4 Ester hydrolases +
Interacting Target Name Dual specificity protein phosphatase 1 (DUSP1) Clinical trial Target Interacting Protein Info
UniProt ID
DUS1_HUMAN 
Synonyms VH1; PTPN10; Protein-tyrosine phosphatase CL100; MKP-1; MKP1; Mitogen-activated protein kinase phosphatase 1; MAP kinase phosphatase-1; MAP kinase phosphatase 1; Dual specificity protein phosphatase hVH1; CL100
Evidence Score (E-score) 5 Experimental Evidences +
1 Affinity Capture-MS [23]
2 Affinity Capture-Western [24]
3 Affinity Capture-Western [25]
4 Co-localization [26]
5 Yeast two hybrid [27]
Interacting Protein Name Dual specificity protein phosphatase 16 (DUSP16) Interacting Protein Interacting Protein Info
UniProt ID
DUS16_HUMAN 
Synonyms MKP.7; MKP7
Evidence Score (E-score) 5 Experimental Evidences +
1 Affinity Capture-MS [28]
2 Affinity Capture-MS [29]
3 Affinity Capture-Western [24]
4 Reconstituted Complex [24]
5 Yeast two hybrid [27]
Interacting Target Name Dual specificity protein phosphatase 10 (DUSP10) Literature-reported Target Interacting Protein Info
UniProt ID
DUS10_HUMAN 
Synonyms MKP-5; MKP5; Mitogen-activated protein kinase phosphatase 5; MAP kinase phosphatase 5
Evidence Score (E-score) 4 Experimental Evidences +
1 Affinity Capture-Western [24]
2 Affinity Capture-Western [30]
3 Reconstituted Complex [24]
4 Yeast two hybrid [27]
Interacting Protein Name Dual specificity protein phosphatase 9 (DUSP9) Interacting Protein Interacting Protein Info
UniProt ID
DUS9_HUMAN 
Synonyms MKP-4; MKP4; Mitogen-activated protein kinase phosphatase 4; MAP kinase phosphatase 4; Dual specificity protein phosphatase 9
Evidence Score (E-score) 4 Experimental Evidences +
1 Affinity Capture-MS [28]
2 Affinity Capture-MS [29]
3 Affinity Capture-MS [31]
4 Reconstituted Complex [1]
Kinases [+] 11 Kinases +
Interacting Target Name MAPK-activated protein kinase 2 (MAPKAPK2) Clinical trial Target Interacting Protein Info
UniProt ID
MAPK2_HUMAN 
Synonyms MK-2; MK2; MAPKAP-K2; MAPKAPK-2; MAPKAP kinase 2; MAPKactivated protein kinase 2; MAP kinase-activated protein kinase 2; MAP kinaseactivated protein kinase 2
Evidence Score (E-score) 13 Experimental Evidences +
1 Affinity Capture-MS [28]
2 Affinity Capture-MS [32]
3 Affinity Capture-MS [29]
4 Affinity Capture-MS [33]
5 Affinity Capture-MS [31]
6 Affinity Capture-MS [34]
7 Affinity Capture-Western [35]
8 Biochemical Activity [36]
9 Co-crystal Structure [37]
10 Co-localization [26]
11 Protein-Fragment Complementation Assay [38]
12 Reconstituted Complex [35]
13 Yeast two hybrid [39]
Interacting Target Name MAPK-activated protein kinase 3 (MAPKAPK3) Literature-reported Target Interacting Protein Info
UniProt ID
MAPK3_HUMAN 
Synonyms MAPKAPK3
Evidence Score (E-score) 8 Experimental Evidences +
1 Affinity Capture-MS [28]
2 Affinity Capture-MS [32]
3 Affinity Capture-MS [29]
4 Affinity Capture-MS [33]
5 Affinity Capture-MS [31]
6 Affinity Capture-MS [34]
7 Biochemical Activity [40]
8 Co-localization [26]
Interacting Protein Name Ribosomal protein S6 kinase alpha-4 (RPS6KA4) Interacting Protein Interacting Protein Info
UniProt ID
KS6A4_HUMAN 
Synonyms MSK2; RSK.B
Evidence Score (E-score) 7 Experimental Evidences +
1 Affinity Capture-MS [28]
2 Affinity Capture-MS [32]
3 Affinity Capture-MS [29]
4 Affinity Capture-MS [31]
5 Affinity Capture-Western [41]
6 Biochemical Activity [41]
7 Yeast two hybrid [41]
Interacting Target Name MAPK signal-integrating kinase 1 (MKNK1) Clinical trial Target Interacting Protein Info
UniProt ID
MKNK1_HUMAN 
Synonyms Mnk1; MAPK signal-integrating kinase 1; MAP kinase signal-integrating kinase 1
Evidence Score (E-score) 6 Experimental Evidences +
1 Affinity Capture-MS [28]
2 Affinity Capture-MS [29]
3 Affinity Capture-MS [31]
4 Affinity Capture-MS [34]
5 Affinity Capture-Western [30]
6 Yeast two hybrid [27]
Interacting Target Name MAP kinase signal-integrating kinase 2 (MKNK2) Clinical trial Target Interacting Protein Info
UniProt ID
MKNK2_HUMAN 
Synonyms Mnk2; MAPK signal-integrating kinase 2; MAP kinase signal-integrating kinase 2
Evidence Score (E-score) 5 Experimental Evidences +
1 Affinity Capture-MS [28]
2 Affinity Capture-MS [29]
3 Affinity Capture-MS [31]
4 Co-localization [26]
5 Yeast two hybrid [27]
Interacting Protein Name Dual specificity mitogen-activated protein kinase kinase 3 (MAP2K3) Interacting Protein Interacting Protein Info
UniProt ID
MP2K3_HUMAN 
Synonyms MAPKK3; MEK3; MKK3; PRKMK3; SAPKK.2; SAPKK2
Evidence Score (E-score) 5 Experimental Evidences +
1 Affinity Capture-MS [28]
2 Affinity Capture-MS [29]
3 Affinity Capture-MS [31]
4 Affinity Capture-Western [42]
5 Fluorescence Resonance Energy Transfer [43]
Interacting Target Name RAC-alpha serine/threonine-protein kinase (AKT1) Successful Target Interacting Protein Info
UniProt ID
AKT1_HUMAN 
Synonyms RAC-PK-alpha; RAC; Proto-oncogene c-Akt; Protein kinase B alpha; Protein kinase B; PKB alpha; PKB
Evidence Score (E-score) 4 Experimental Evidences +
1 Affinity Capture-Western [35]
2 Biochemical Activity [35]
3 Biochemical Activity [44]
4 Fluorescence Resonance Energy Transfer [43]
Interacting Target Name Extracellular signal-regulated kinase 2 (ERK2) Clinical trial Target Interacting Protein Info
UniProt ID
MK01_HUMAN 
Synonyms PRKM2; PRKM1; P42-MAPK; P42 Mitogen-activated protein kinase; Mitogen-activated protein kinase 2; Mitogen-activated protein kinase 1; MAPK 2; MAPK 1; MAP kinase isoform p42; MAP kinase 2; MAP kinase 1; ERT1; ERK-2
Evidence Score (E-score) 4 Experimental Evidences +
1 Affinity Capture-Western [45]
2 Affinity Capture-Western [30]
3 Affinity Capture-Western [46]
4 Protein-Fragment Complementation Assay [38]
Interacting Target Name Ribosomal protein S6 kinase alpha-5 (RSK5) Patented-recorded Target Interacting Protein Info
UniProt ID
KS6A5_HUMAN 
Synonyms S6K-alpha-5; RSK-like protein kinase; RSKL; Nuclear mitogen- and stress-activated protein kinase 1; MSK1; 90 kDa ribosomal protein S6 kinase 5
Evidence Score (E-score) 4 Experimental Evidences +
1 Affinity Capture-MS [28]
2 Affinity Capture-MS [29]
3 Affinity Capture-Western [30]
4 Yeast two hybrid [27]
Interacting Target Name Stress-activated protein kinase 2b (p38 beta) Clinical trial Target Interacting Protein Info
UniProt ID
MK11_HUMAN 
Synonyms Stress-activated protein kinase-2; SAPK2b; SAPK2; PRKM11; P38b; P38-2; P38 Mitogen-activated protein kinase beta; Mitogen-activated protein kinase p38 beta; Mitogen-activated protein kinase 11; MAPK 11; MAP kinase p38 beta; MAP kinase 11
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [31]
2 Yeast two hybrid [47]
Interacting Target Name Extracellular signal-regulated kinase 1 (ERK1) Clinical trial Target Interacting Protein Info
UniProt ID
MK03_HUMAN 
Synonyms PRKM3; P44-MAPK; P44-ERK1; P44 Mitogen-activated protein kinase; Mitogen-activated protein kinase 3; Microtubule-associated protein-2 kinase; Microtubule-associated protein 2 kinase; MAPK 3; MAP kinase isoform p44; MAP kinase 3; Insulin-stimulated MAP2 kinase; ERT2; ERK-1
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [45]
2 Protein-Fragment Complementation Assay [38]
Pore-forming toxins [+] 1 Pore-forming toxins +
Interacting Target Name Cellular tumor antigen p53 (TP53) Clinical trial Target Interacting Protein Info
UniProt ID
P53_HUMAN 
Synonyms Tumor suppressor p53; Phosphoprotein p53; P53; Antigen NY-CO-13
Evidence Score (E-score) 7 Experimental Evidences +
1 Affinity Capture-Western [48]
2 Affinity Capture-Western [49]
3 Affinity Capture-Western [50]
4 Biochemical Activity [50]
5 Biochemical Activity [6]
6 Biochemical Activity [49]
7 Protein-Fragment Complementation Assay [38]
Transcription regulators [+] 1 Transcription regulators +
Interacting Protein Name Myocyte-specific enhancer factor 2D (MEF2D) Interacting Protein Interacting Protein Info
UniProt ID
MEF2D_HUMAN 
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-MS [28]
2 Affinity Capture-MS [29]
3 Yeast two hybrid [27]
Other proteins [+] 5 Other proteins +
Interacting Protein Name ELM2 and SANT domain-containing protein 1 (ELMSAN1) Interacting Protein Interacting Protein Info
UniProt ID
EMSA1_HUMAN 
Synonyms C14orf117; C14orf43; LSR68; c14_5541
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-MS [28]
2 Affinity Capture-MS [29]
3 Yeast two hybrid [27]
Interacting Protein Name TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 (TAB1) Interacting Protein Interacting Protein Info
UniProt ID
TAB1_HUMAN 
Synonyms 3.Tab1; MAP3K7IP1
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-Western [17]
2 Affinity Capture-Western [51]
3 Co-localization [26]
Interacting Protein Name Transcription factor SPT20 homolog (SUPT20H) Interacting Protein Interacting Protein Info
UniProt ID
SP20H_HUMAN 
Synonyms C13; C13orf19; FAM48A; P38IP; SPT20
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [52]
2 Yeast two hybrid [27]
Interacting Protein Name Hamartin (TSC1) Interacting Protein Interacting Protein Info
UniProt ID
TSC1_HUMAN 
Synonyms LAM; TSC
Evidence Score (E-score) 2 Experimental Evidences +
1 Fluorescence Resonance Energy Transfer [43]
2 Yeast two hybrid [53]
Interacting Protein Name Zinc finger HIT domain-containing protein 1 (ZNHIT1) Interacting Protein Interacting Protein Info
UniProt ID
ZNHI1_HUMAN 
Synonyms CG1I; ZNFN4A1
Evidence Score (E-score) 2 Experimental Evidences +
1 Biochemical Activity [54]
2 Yeast two hybrid [55]
References  Top
REF 1 Catalytic activation of the phosphatase MKP-3 by ERK2 mitogen-activated protein kinase. Science. 1998 May 22;280(5367):1262-5.
REF 2 Phosphorylation of Plk1 at Ser326 regulates its functions during mitotic progression. Oncogene. 2008 Nov 6;27(52):6635-45.
REF 3 Acetylation of a conserved lysine residue in the ATP binding pocket of p38 augments its kinase activity during hypertrophy of cardiomyocytes. Mol Cell Biol. 2011 Jun;31(11):2349-63.
REF 4 Regulation of stress-responsive mitogen-activated protein (MAP) kinase pathways by TAO2. J Biol Chem. 2001 May 11;276(19):16070-5.
REF 5 Characterization of the mitogen-activated protein kinase kinase 4 (MKK4)/c-Jun NH2-terminal kinase 1 and MKK3/p38 pathways regulated by MEK kinases 2 and 3. MEK kinase 3 activates MKK3 but does not cause activation of p38 kinase in vivo. J Biol Chem. 1997 May 30;272(22):14489-96.
REF 6 DJ-1 modulates the p38 mitogen-activated protein kinase pathway through physical interaction with apoptosis signal-regulating kinase 1. J Cell Biochem. 2010 May;110(1):229-37.
REF 7 CIIA negatively regulates neuronal cell death induced by oxygen-glucose deprivation and reoxygenation. Mol Cell Biochem. 2014 Dec;397(1-2):139-46.
REF 8 The p38 pathway provides negative feedback for Ras proliferative signaling. J Biol Chem. 2000 Dec 15;275(50):38973-80.
REF 9 Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine. J Biol Chem. 1995 Mar 31;270(13):7420-6.
REF 10 P38MAPK-dependent phosphorylation and degradation of SRC-3/AIB1 and RARalpha-mediated transcription. EMBO J. 2006 Feb 22;25(4):739-51.
REF 11 p62 functions as a p38 MAP kinase regulator. Biochem Biophys Res Commun. 2000 Mar 16;269(2):521-5.
REF 12 Protein kinase C-delta (PKC-delta ) is activated by type I interferons and mediates phosphorylation of Stat1 on serine 727. J Biol Chem. 2002 Apr 26;277(17):14408-16.
REF 13 p38-2, a novel mitogen-activated protein kinase with distinct properties. J Biol Chem. 1997 Aug 1;272(31):19509-17.
REF 14 AKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1: implication of AKT2 in chemoresistance. J Biol Chem. 2003 Jun 27;278(26):23432-40.
REF 15 MAPK-activated protein kinase-2 participates in p38 MAPK-dependent and ERK-dependent functions in human neutrophils. Cell Signal. 2003 Nov;15(11):993-1001.
REF 16 Tristetraprolin (TTP)-14-3-3 complex formation protects TTP from dephosphorylation by protein phosphatase 2a and stabilizes tumor necrosis factor-alpha mRNA. J Biol Chem. 2007 Feb 9;282(6):3766-77.
REF 17 Ubiquitin plays an atypical role in GPCR-induced p38 MAP kinase activation on endosomes. J Cell Biol. 2015 Sep 28;210(7):1117-31.
REF 18 Expression of COX-2 in platelet-monocyte interactions occurs via combinatorial regulation involving adhesion and cytokine signaling. J Clin Invest. 2006 Oct;116(10):2727-38.
REF 19 The activation state of p38 mitogen-activated protein kinase determines the efficiency of ATP competition for pyridinylimidazole inhibitor binding. Biochemistry. 1998 Sep 29;37(39):13846-53.
REF 20 Tighter C-helix-L16-helix interactions seem to make p38 less prone to activation by autophosphorylation than Hog1. Biosci Rep. 2016 Apr 27;36(2). pii: e00324.
REF 21 MAPK p38 regulates transcriptional activity of NF-kappaB in primary human astrocytes via acetylation of p65. J Immunol. 2007 Nov 15;179(10):7101-9.
REF 22 Specific regulation of cytokine-dependent p38 MAP kinase activation by p62/SQSTM1. J Biochem. 2008 Jun;143(6):765-72.
REF 23 Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators. Cell Rep. 2016 Nov 22;17(9):2488-2501.
REF 24 A Novel MAPK phosphatase MKP-7 acts preferentially on JNK/SAPK and p38 alpha and beta MAPKs. J Biol Chem. 2001 Jul 13;276(28):26629-39.
REF 25 Distinct binding determinants for ERK2/p38alpha and JNK map kinases mediate catalytic activation and substrate selectivity of map kinase phosphatase-1. J Biol Chem. 2001 May 11;276(19):16491-500.
REF 26 Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network. J Proteome Res. 2014 Dec 5;13(12):5339-46.
REF 27 A human MAP kinase interactome. Nat Methods. 2010 Oct;7(10):801-5.
REF 28 Architecture of the human interactome defines protein communities and disease networks. Nature. 2017 May 25;545(7655):505-509.
REF 29 The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell. 2015 Jul 16;162(2):425-440.
REF 30 Identification of a docking groove on ERK and p38 MAP kinases that regulates the specificity of docking interactions. EMBO J. 2001 Feb 1;20(3):466-79.
REF 31 The protein interaction landscape of the human CMGC kinase group. Cell Rep. 2013 Apr 25;3(4):1306-20.
REF 32 Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy. Sci Signal. 2015 Apr 7;8(371):rs3.
REF 33 A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Cell. 2015 Oct 22;163(3):712-23.
REF 34 Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. Nat Methods. 2013 Apr;10(4):307-14.
REF 35 p38 Kinase-dependent MAPKAPK-2 activation functions as 3-phosphoinositide-dependent kinase-2 for Akt in human neutrophils. J Biol Chem. 2001 Feb 2;276(5):3517-23.
REF 36 Identification of two distinct regions of p38 MAPK required for substrate binding and phosphorylation. Biochem Biophys Res Commun. 1999 Dec 9;266(1):284-9.
REF 37 Molecular basis of MAPK-activated protein kinase 2:p38 assembly. Proc Natl Acad Sci U S A. 2007 Apr 10;104(15):6353-8.
REF 38 Monitoring protein-protein interactions in mammalian cells by trans-SUMOylation. Biochem J. 2011 Sep 15;438(3):495-503.
REF 39 Toward an understanding of the protein interaction network of the human liver. Mol Syst Biol. 2011 Oct 11;7:536.
REF 40 MRP8 and MRP14 control microtubule reorganization during transendothelial migration of phagocytes. Blood. 2004 Dec 15;104(13):4260-8.
REF 41 RSK-B, a novel ribosomal S6 kinase family member, is a CREB kinase under dominant control of p38alpha mitogen-activated protein kinase (p38alphaMAPK). J Biol Chem. 1998 Nov 6;273(45):29661-71.
REF 42 Mxi2 promotes stimulus-independent ERK nuclear translocation. EMBO J. 2007 Feb 7;26(3):635-46.
REF 43 OncoPPi-informed discovery of mitogen-activated protein kinase kinase 3 as a novel binding partner of c-Myc. Oncogene. 2017 Oct 19;36(42):5852-5860.
REF 44 Constitutive c-jun N-terminal kinase activity in acute myeloid leukemia derives from Flt3 and affects survival and proliferation. Exp Hematol. 2006 Oct;34(10):1360-76.
REF 45 p38alpha isoform Mxi2 binds to extracellular signal-regulated kinase 1 and 2 mitogen-activated protein kinase and regulates its nuclear activity by sustaining its phosphorylation levels. Mol Cell Biol. 2003 May;23(9):3079-90.
REF 46 PAK is regulated by PI3K, PIX, CDC42, and PP2Calpha and mediates focal adhesion turnover in the hyperosmotic stress-induced p38 pathway. J Biol Chem. 2008 Sep 5;283(36):24949-61.
REF 47 A directed protein interaction network for investigating intracellular signal transduction. Sci Signal. 2011 Sep 6;4(189):rs8.
REF 48 TGFbeta1-induced activation of ATM and p53 mediates apoptosis in a Smad7-dependent manner. Cell Cycle. 2006 Dec;5(23):2787-95.
REF 49 Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation. EMBO J. 1999 Dec 1;18(23):6845-54.
REF 50 Essential role of p53 phosphorylation by p38 MAPK in apoptosis induction by the HIV-1 envelope. J Exp Med. 2005 Jan 17;201(2):279-89.
REF 51 TAB1beta (transforming growth factor-beta-activated protein kinase 1-binding protein 1beta ), a novel splicing variant of TAB1 that interacts with p38alpha but not TAK1. J Biol Chem. 2003 Jan 24;278(4):2286-93.
REF 52 Coordinated regulation of autophagy by p38alpha MAPK through mAtg9 and p38IP. EMBO J. 2010 Jan 6;29(1):27-40.
REF 53 Interactome mapping of the phosphatidylinositol 3-kinase-mammalian target of rapamycin pathway identifies deformed epidermal autoregulatory factor-1 as a new glycogen synthase kinase-3 interactor. Mol Cell Proteomics. 2010 Jul;9(7):1578-93.
REF 54 A new p38 MAP kinase-regulated transcriptional coactivator that stimulates p53-dependent apoptosis. EMBO J. 2007 Apr 18;26(8):2115-26.
REF 55 Protein interaction data set highlighted with human Ras-MAPK/PI3K signaling pathways. J Proteome Res. 2008 Sep;7(9):3879-89.

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