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| Target General Information |
Top |
| Target ID |
T67883 |
Target Info
|
| Target Name |
Decorin (DCN) |
| Synonyms |
SLRR1B; PGS2; PG40; PG-S2; Bone proteoglycan II |
| Target Type |
Literature-reported Target |
| Gene Name |
DCN |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Kinases |
[+] 1 Kinases |
+ |
| Interacting Target Name |
Epidermal growth factor receptor (EGFR) |
Successful Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
Epidermal growth factor receptor variant III; Proto-oncogene c-ErbB-1 variant III; Receptor tyrosine-protein kinase erbB-1 variant III; EGFR variant III; ERBB variant III; ERBB1 variant III; HER1 variant III |
| Evidence Score (E-score) |
3 Experimental Evidences |
+ |
| 1 |
Reconstituted Complex |
[1] |
| 2 |
Reconstituted Complex |
[2] |
| 3 |
Yeast two hybrid |
[1] |
| References |
Top |
| REF 1 |
Decorin binds to a narrow region of the epidermal growth factor (EGF) receptor, partially overlapping but distinct from the EGF-binding epitope. J Biol Chem. 2002 Sep 20;277(38):35671-81.
|
| REF 2 |
Decorin is a biological ligand for the epidermal growth factor receptor. J Biol Chem. 1999 Feb 19;274(8):4489-92.
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