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| Target General Information |
Top |
| Target ID |
T68383 |
Target Info
|
| Target Name |
Bone morphogenetic protein 2 (BMP2) |
| Synonyms |
Bone morphogenetic protein 2A; BMP2A; BMP-2A; BMP-2 |
| Target Type |
Clinical trial Target |
| Gene Name |
BMP2 |
| Biochemical Class |
Growth factor |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Kinases |
[+] 1 Kinases |
+ |
| Interacting Target Name |
Bone morphogenetic protein receptor (BMPR2) |
Literature-reported Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
PPH1; Bone morphogenetic protein receptor type-2; Bone morphogenetic protein receptor type II; BMPR-II; BMPR-2; BMP type-2 receptor; BMP type II receptor |
| Evidence Score (E-score) |
3 Experimental Evidences |
+ |
| 1 |
Affinity Capture-Western |
[1] |
| 2 |
Reconstituted Complex |
[2] |
| 3 |
Reconstituted Complex |
[3] |
| References |
Top |
| REF 1 |
Human type II receptor for bone morphogenic proteins (BMPs): extension of the two-kinase receptor model to the BMPs. Mol Cell Biol. 1995 Jul;15(7):3479-86.
|
| REF 2 |
BMP-2 antagonists emerge from alterations in the low-affinity binding epitope for receptor BMPR-II. EMBO J. 2000 Jul 3;19(13):3314-24.
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| REF 3 |
Bone morphogenetic protein receptor complexes on the surface of live cells: a new oligomerization mode for serine/threonine kinase receptors. Mol Biol Cell. 2000 Mar;11(3):1023-35.
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