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| Target General Information |
Top |
| Target ID |
T77664 |
Target Info
|
| Target Name |
Interferon-gamma (IFNG) |
| Synonyms |
Interferon gamma; Immune interferon; IFN-gamma |
| Target Type |
Successful Target |
| Gene Name |
IFNG |
| Biochemical Class |
Cytokine: interferon |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Cytokine receptors |
[+] 1 Cytokine receptors |
+ |
| Interacting Protein Name |
Interferon gamma receptor 1 (IFNGR1) |
Interacting Protein |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
CD119; IFNGR; IMD27A; IMD27B |
| Evidence Score (E-score) |
3 Experimental Evidences |
+ |
| 1 |
Affinity Capture-MS |
[1] |
| 2 |
Co-crystal Structure |
[2] |
| 3 |
Reconstituted Complex |
[3] |
| References |
Top |
| REF 1 |
Architecture of the human interactome defines protein communities and disease networks. Nature. 2017 May 25;545(7655):505-509.
|
| REF 2 |
Observation of an unexpected third receptor molecule in the crystal structure of human interferon-gamma receptor complex. Structure. 2000 Sep 15;8(9):927-36.
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| REF 3 |
Interaction between the components of the interferon gamma receptor complex. J Biol Chem. 1995 Sep 8;270(36):20915-21.
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