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| Target General Information |
Top |
| Target ID |
T79821 |
Target Info
|
| Target Name |
Calreticulin (CALR) |
| Synonyms |
grp60; HACBP; Endoplasmic reticulum resident protein 60; ERp60; ERC; Calregulin; CRTC; CRP55 |
| Target Type |
Literature-reported Target |
| Gene Name |
CALR |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| G-protein-coupled receptors |
[+] 1 G-protein-coupled receptors |
+ |
| Interacting Target Name |
Melatonin receptor type 1A (MTNR1A) |
Successful Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
Mel-1A-R; Mel1AR; Mel1a receptor |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Affinity Capture-MS |
[1] |
| 2 |
Reconstituted Complex |
[2] |
| Histones |
[+] 1 Histones |
+ |
| Interacting Target Name |
Gamma-Histone H2AX (H2AFX) |
Literature-reported Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
Phosphorylation of H2AX; Histone H2AX; Histone H2A.x; H2AX; H2a/x |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Affinity Capture-MS |
[3] |
| 2 |
Affinity Capture-Western |
[3] |
| References |
Top |
| REF 1 |
Purification and identification of G protein-coupled receptor protein complexes under native conditions. Mol Cell Proteomics. 2007 May;6(5):835-44.
|
| REF 2 |
Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons. J Pineal Res. 2016 Jan;60(1):95-108.
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| REF 3 |
The dynamic alterations of H2AX complex during DNA repair detected by a proteomic approach reveal the critical roles of Ca(2+)/calmodulin in the ionizing radiation-induced cell cycle arrest. Mol Cell Proteomics. 2006 Jun;5(6):1033-44.
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