Target Interacting Protein Information

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Target General Information
Target Interacting Proteins
References
Target General Information  Top
Target ID T80853 Target Info
Target Name Laminin receptor 37/67kDa (LRP/LR)
Synonyms Small ribosomal subunit protein uS2; NEM/1CHD4; Multidrug resistance-associated protein MGr1-Ag; Laminin-binding protein precursor p40; Laminin receptor 1; LamR; LBP/p40; LAMR1; LAMBR; Colon carcinoma laminin-binding protein; 67LR; 67 kDa laminin receptor; 40S ribosomal protein SA; 37LRP; 37/67 kDa laminin receptor; 37 kDa laminin receptor precursor
Target Type Patented-recorded Target
Gene Name RPSA
UniProt ID
RSSA_HUMAN 
Target Interacting Proteins  Top
Acid anhydride hydrolases [+] 1 Acid anhydride hydrolases +
Interacting Protein Name Pre-rRNA-processing protein TSR1 homolog (TSR1) Interacting Protein Interacting Protein Info
UniProt ID
TSR1_HUMAN 
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-MS [1]
2 Co-fractionation [2]
Ribosomal proteins [+] 1 Ribosomal proteins +
Interacting Protein Name Small ribosomal subunit protein eS21 (RPS21) Interacting Protein Interacting Protein Info
UniProt ID
RS21_HUMAN 
Synonyms HLDF; S21
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-MS [3]
2 Affinity Capture-MS [1]
3 Yeast two hybrid [4]
Other proteins [+] 1 Other proteins +
Interacting Target Name Beta-catenin (CTNNB1) Successful Target Interacting Protein Info
UniProt ID
CTNB1_HUMAN 
Synonyms Wnt/beta-catenin signaling pathway; PRO2286; OK/SW-cl.35; CTNNB; Catenin beta-1
Evidence Score (E-score) 1 Experimental Evidences +
1 Affinity Capture-MS [5]
References  Top
REF 1 The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell. 2015 Jul 16;162(2):425-440.
REF 2 A high-throughput approach for measuring temporal changes in the interactome. Nat Methods. 2012 Sep;9(9):907-9.
REF 3 Architecture of the human interactome defines protein communities and disease networks. Nature. 2017 May 25;545(7655):505-509.
REF 4 Ribosome-associated protein LBP/p40 binds to S21 protein of 40S ribosome: analysis using a yeast two-hybrid system. Biochem Biophys Res Commun. 1999 Mar 16;256(2):385-90.
REF 5 Proteomic analysis identifies that 14-3-3zeta interacts with beta-catenin and facilitates its activation by Akt. Proc Natl Acad Sci U S A. 2004 Oct 26;101(43):15370-5.

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