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| Target General Information |
Top |
| Target ID |
T83905 |
Target Info
|
| Target Name |
Placental cadherin (CDH3) |
| Synonyms |
Pcadherin; P-cadherin; Cadherin-3; CDHP |
| Target Type |
Clinical trial Target |
| Gene Name |
CDH3 |
| Biochemical Class |
Cadherin protein |
| UniProt ID |
|
| Target Interacting Proteins |
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| Other proteins |
[+] 1 Other proteins |
+ |
| Interacting Target Name |
Beta-catenin (CTNNB1) |
Successful Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
Wnt/beta-catenin signaling pathway; PRO2286; OK/SW-cl.35; CTNNB; Catenin beta-1 |
| Evidence Score (E-score) |
4 Experimental Evidences |
+ |
| 1 |
Affinity Capture-MS |
[1] |
| 2 |
Affinity Capture-Western |
[2] |
| 3 |
Affinity Capture-Western |
[3] |
| 4 |
Co-purification |
[2] |
| References |
Top |
| REF 1 |
Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in -Catenin-Active Cancers. Cell Syst. 2016 Sep 28;3(3):302-316.e4.
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| REF 2 |
Amino-terminal domain of classic cadherins determines the specificity of the adhesive interactions. J Cell Sci. 2000 Aug;113 ( Pt 16):2829-36.
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| REF 3 |
P-cadherin functional role is dependent on E-cadherin cellular context: a proof of concept using the breast cancer model. J Pathol. 2013 Apr;229(5):705-18.
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