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| Target General Information |
Top |
| Target ID |
T89299 |
Target Info
|
| Target Name |
Fos-related antigen 1 (FOSL1) |
| Synonyms |
Fra-1; FRA1 |
| Target Type |
Literature-reported Target |
| Gene Name |
FOSL1 |
| Biochemical Class |
Basic leucine zipper bZIP |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Transcription regulators |
[+] 1 Transcription regulators |
+ |
| Interacting Target Name |
Transcription factor AP-1 (JUN) |
Discontinued Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
V-jun avian sarcoma virus 17 oncogene homolog; Transcription factor AP-1; Proto-oncogene c-jun; P39; C-jun proto-oncogene; AP-1 transcription factor; AP1; Activator protein-1; Activator protein 1 |
| Evidence Score (E-score) |
4 Experimental Evidences |
+ |
| 1 |
Affinity Capture-Western |
[1] |
| 2 |
Fluorescence Resonance Energy Transfer |
[2] |
| 3 |
Reconstituted Complex |
[3] |
| 4 |
Yeast two hybrid |
[3] |
| References |
Top |
| REF 1 |
Ten ERK-related proteins in three distinct classes associate with AP-1 proteins and/or AP-1 DNA. J Biol Chem. 2001 Aug 24;276(34):32362-72.
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| REF 2 |
Networks of bZIP protein-protein interactions diversified over a billion years of evolution. Science. 2013 May 10;340(6133):730-4.
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| REF 3 |
Cross-family interaction between the bHLHZip USF and bZip Fra1 proteins results in down-regulation of AP1 activity. Oncogene. 1997 May 1;14(17):2091-8.
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