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| Target General Information |
Top |
| Target ID |
T91130 |
Target Info
|
| Target Name |
LDL receptor related protein-1 (LRP-1) |
| Synonyms |
Alpha-2-macroglobulin receptor; A2MR |
| Target Type |
Literature-reported Target |
| Gene Name |
LRP1 |
| Biochemical Class |
Low density lipoprotein receptor |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Kinases |
[+] 1 Kinases |
+ |
| Interacting Target Name |
Epidermal growth factor receptor (EGFR) |
Successful Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
Epidermal growth factor receptor variant III; Proto-oncogene c-ErbB-1 variant III; Receptor tyrosine-protein kinase erbB-1 variant III; EGFR variant III; ERBB variant III; ERBB1 variant III; HER1 variant III |
| Evidence Score (E-score) |
3 Experimental Evidences |
+ |
| 1 |
Affinity Capture-MS |
[1] |
| 2 |
Protein-Fragment Complementation Assay |
[2] |
| 3 |
Yeast two hybrid |
[3] |
| References |
Top |
| REF 1 |
A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome. Mol Cell. 2017 Jan 19;65(2):347-360.
|
| REF 2 |
The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells. Nat Methods. 2014 May;11(5):585-92.
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| REF 3 |
In silico prediction of physical protein interactions and characterization of interactome orphans. Nat Methods. 2015 Jan;12(1):79-84.
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