Target Interacting Protein Information

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Target General Information
Target Interacting Proteins
References
Target General Information  Top
Target ID T91331 Target Info
Target Name Fibroblast growth factor receptor 3 (FGFR3)
Synonyms JTK4; FGFR-3; CD333
Target Type Successful Target
Gene Name FGFR3
Biochemical Class Kinase
UniProt ID
FGFR3_HUMAN 
Target Interacting Proteins  Top
Adapter proteins [+] 1 Adapter proteins +
Interacting Protein Name Growth factor receptor-bound protein 2 (GRB2) Interacting Protein Interacting Protein Info
UniProt ID
GRB2_HUMAN 
Synonyms SH2/SH3 adapter GRB2; Protein Ash; Growth factor receptor-bound protein 2; ASH; Adapter protein GRB2
Evidence Score (E-score) 2 Experimental Evidences +
1 Affinity Capture-Western [1]
2 Co-fractionation [2]
Growth factors [+] 1 Growth factors +
Interacting Protein Name Fibroblast growth factor 9 (FGF9) Interacting Protein Interacting Protein Info
UniProt ID
FGF9_HUMAN 
Synonyms FGF.9; GAF; HBFG.9; HBGF.9; SYNS3
Evidence Score (E-score) 3 Experimental Evidences +
1 Affinity Capture-Western [3]
2 Reconstituted Complex [4]
3 Reconstituted Complex [3]
References  Top
REF 1 Signal transduction pathway of human fibroblast growth factor receptor 3. Identification of a novel 66-kDa phosphoprotein. J Biol Chem. 1997 Mar 7;272(10):6621-8.
REF 2 Panorama of ancient metazoan macromolecular complexes. Nature. 2015 Sep 17;525(7569):339-44.
REF 3 Mapping ligand binding domains in chimeric fibroblast growth factor receptor molecules. Multiple regions determine ligand binding specificity. J Biol Chem. 1999 Dec 3;274(49):34785-94.
REF 4 Expression and biological activity of mouse fibroblast growth factor-9. J Biol Chem. 1996 Jan 19;271(3):1726-31.

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