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| Target General Information |
Top |
| Target ID |
T92635 |
Target Info
|
| Target Name |
GATA-binding factor 3 (GATA3) |
| Synonyms |
Trans-acting T-cell-specific transcription factor GATA-3 |
| Target Type |
Literature-reported Target |
| Gene Name |
GATA3 |
| Biochemical Class |
Zinc-finger |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Carbon-nitrogen hydrolases |
[+] 1 Carbon-nitrogen hydrolases |
+ |
| Interacting Target Name |
Histone deacetylase 3 (HDAC3) |
Clinical trial Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
SMAP45; RPD3-2; RPD32; HD3 |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Affinity Capture-Western |
[1] |
| 2 |
Reconstituted Complex |
[2] |
| References |
Top |
| REF 1 |
Interaction of GATA-3/T-bet transcription factors regulates expression of sialyl Lewis X homing receptors on Th1/Th2 lymphocytes. Proc Natl Acad Sci U S A. 2006 Nov 7;103(45):16894-9.
|
| REF 2 |
GATA3 acetylation at K119 by CBP inhibits cell migration and invasion in lung adenocarcinoma. Biochem Biophys Res Commun. 2018 Mar 4;497(2):633-638.
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