Target Validation Information
TTD ID T31543
Target Name Suppressor of tumorigenicity 14 protein (ST14)
Type of Target
Patented-recorded
Drug Potency against Target 2-nas-phe(3-am)-4-(2-guanidinoethyl)piperidine Drug Info Ki = 46 nM [1]
3-tapap Drug Info Ki = 14000 nM [1]
References
REF 1 Secondary amides of sulfonylated 3-amidinophenylalanine. New potent and selective inhibitors of matriptase. J Med Chem. 2006 Jul 13;49(14):4116-26.

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