Target Validation Information
TTD ID T55293
Target Name Integrin alpha-2 (ITGA2)
Type of Target
Clinical trial
Drug Potency against Target 3-(3-(benzamido)-5-nitrobenzamido)propanoic acid Drug Info IC50 = 32 nM [1]
3-(3-(carbamoyl)benzamido)-3-phenylpropanoic acid Drug Info IC50 = 1 nM [1]
3-(3-(carbamoyl)benzamido)propanoic acid Drug Info IC50 = 9 nM [1]
References
REF 1 Derivatives of 7-amino-1,2,3,4-tetrahydroisoquinoline and isophthalic acids as novel fibrinogen receptor antagonists. Bioorg Med Chem Lett. 2006 Oct 15;16(20):5294-7.

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