| Target Validation Information | |||||
|---|---|---|---|---|---|
| TTD ID | T68227 | ||||
| Target Name | c-Jun messenger RNA (c-Jun mRNA) | ||||
| Type of Target |
Literature-reported |
||||
| Drug Potency against Target | Drug Info | IC50 = 1067 nM | [1] | ||
| Pergularinine | Drug Info | IC50 = 110 nM | [1] | ||
| [(R)-(+)-deoxytylophorinidine | Drug Info | IC50 = 68 nM | [1] | ||
| References | |||||
| REF 1 | Structure-activity studies of phenanthroindolizidine alkaloids as potential antitumor agents. Bioorg Med Chem Lett. 2007 Aug 1;17(15):4338-42. | ||||
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