Resistance mutation info of target
Target General Information | ||||||||||||||||||
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Target ID | T24634 | |||||||||||||||||
Target Name | Bacterial Enoylpyruvate transferase (murA) | |||||||||||||||||
Gene Name | murA | |||||||||||||||||
Species | Escherichia coli | |||||||||||||||||
UniProt ID | MURA_ECOLI | |||||||||||||||||
Sequence |
MDKFRVQGPTKLQGEVTISGAKNAALPILFAALLAEEPVEIQNVPKLKDVDTSMKLLSQL GAKVERNGSVHIDARDVNVFCAPYDLVKTMRASIWALGPLVARFGQGQVSLPGGCTIGAR PVDLHISGLEQLGATIKLEEGYVKASVDGRLKGAHIVMDKVSVGATVTIMCAATLAEGTT IIENAAREPEIVDTANFLITLGAKISGQGTDRIVIEGVERLGGGVYRVLPDRIETGTFLV AAAISRGKIICRNAQPDTLDAVLAKLRDAGADIEVGEDWISLDMHGKRPKAVNVRTAPHP AFPTDMQAQFTLLNLVAEGTGFITETVFENRFMHVPELSRMGAHAEIESNTVICHGVEKL SGAQVMATDLRASASLVLAGCIAEGTTVVDRIYHIDRGYERIEDKLRALGANIERVKGE [Escherichia coli] |
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Drug and Corresponding Resistance Mutations | ||||||||||||||||||
Mutation Info | Missense: D369N | |||||||||||||||||
Drugs |
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Mutation Info | Missense: L370I | |||||||||||||||||
Drugs |
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References | ||||||||||||||||||
REF 1 | CARD 2017: expansion and model-centric curation of the comprehensive antibiotic resistance database. Nucleic Acids Res. 2017 Jan 4;45(D1):D566-D573. |
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