Drug Information

Drug General Information
Drug ID
DX0HJ4
Drug Name
2-(benzo[c][1,2,5]thiadiazole-4-sulfonamido)-4-chloro-N-phenethylbenzamide
Synonyms
CHEMBL569616
Indication Discovery agent Investigative [1587926]
Formula
C21H17ClN4O3S2
Canonical SMILES
Clc1ccc(C(=O)NCCc2ccccc2)c(NS(=O)(=O)c3cccc4nsnc34)c1
InChI
InChI=1S/C21H17ClN4O3S2/c22-15-9-10-16(21(27)23-12-11-14-5-2-1-3-6-14)18(13-15)26-31(28,29)19-8-4-7-17-20(19)25-30-24-17/h1-10,13,26H,11-12H2,(H,23,27)
InChIKey
VYOIZRAKVRLMAX-UHFFFAOYSA-N
Target and Pathway
Target(s) Gastrin/cholecystokinin type B receptor Target Info [1587926]
Cholecystokinin receptor type A Target Info [1587926]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gastric acid secretionhsa04020:Calcium signaling pathway
Insulin secretion
Pancreatic secretion
PANTHER Pathway CCKR signaling map ST
PathWhiz Pathway Gastric Acid Production
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
Gastrin-CREB signalling pathway via PKC and MAPKR-HSA-375276:Peptide ligand-binding receptors
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Secretion of Hydrochloric Acid in Parietal Cells
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
GPCRs, OtherWP455:GPCRs, Class A Rhodopsin-like
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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