Drug Information

Drug General Information
Drug ID
DX1X6R
Drug Name
2-(benzo[c][1,2,5]thiadiazole-4-sulfonamido)-4-chloro-N-(3,4-dichlorophenethyl)benzamide
Synonyms
CHEMBL570521
Indication Discovery agent Investigative [1587926]
Formula
C21H15Cl3N4O3S2
Canonical SMILES
Clc1ccc(C(=O)NCCc2ccc(Cl)c(Cl)c2)c(NS(=O)(=O)c3cccc4nsnc34)c1
InChI
InChI=1S/C21H15Cl3N4O3S2/c22-13-5-6-14(21(29)25-9-8-12-4-7-15(23)16(24)10-12)18(11-13)28-33(30,31)19-3-1-2-17-20(19)27-32-26-17/h1-7,10-11,28H,8-9H2,(H,25,29)
InChIKey
AFKAKAHYZGKTTI-UHFFFAOYSA-N
Target and Pathway
Target(s) Gastrin/cholecystokinin type B receptor Target Info [1587926]
Cholecystokinin receptor type A Target Info [1587926]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gastric acid secretionhsa04020:Calcium signaling pathway
Insulin secretion
Pancreatic secretion
PANTHER Pathway CCKR signaling map ST
PathWhiz Pathway Gastric Acid Production
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
Gastrin-CREB signalling pathway via PKC and MAPKR-HSA-375276:Peptide ligand-binding receptors
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Secretion of Hydrochloric Acid in Parietal Cells
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
GPCRs, OtherWP455:GPCRs, Class A Rhodopsin-like
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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