Drug Information

Drug General Information
Drug ID
DX3XNQ
Drug Name
5-(4-{2-[4-((R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperidin-1-yl]-2-oxo-ethyl}-piperidine-1-carbonyl)-nicotinic acid
Synonyms
CHEMBL315402
Indication Discovery agent Investigative [1587926]
Formula
C33H33Br2ClN4O4
Canonical SMILES
OC(=O)c1cncc(c1)C(=O)N2CCC(CC(=O)N3CCC(CC3)[C@H]4c5ncc(Br)cc5CCc6cc(Cl)cc(Br)c46)CC2
InChI
InChI=1S/C33H33Br2ClN4O4/c34-25-13-22-2-1-21-14-26(36)15-27(35)29(21)30(31(22)38-18-25)20-5-9-39(10-6-20)28(41)11-19-3-7-40(8-4-19)32(42)23-12-24(33(43)44)17-37-16-23/h12-20,30H,1-11H2,(H,43,44)/t30-/m1/s1
InChIKey
BXRDSFHISHNZJF-SSEXGKCCSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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