Drug Information

Drug General Information
Drug ID
DX4DJO
Drug Name
2-(1-Acetyl-piperidin-4-yl)-1-[4-((S)-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-ethanone
Synonyms
CHEMBL355717
Indication Discovery agent Investigative [1587926]
Formula
C27H33ClN4O2
Canonical SMILES
CC(=O)N1CCC(CC(=O)N2CCN(CC2)[C@H]3c4ccc(Cl)cc4CCc5cccnc35)CC1
InChI
InChI=1S/C27H33ClN4O2/c1-19(33)30-11-8-20(9-12-30)17-25(34)31-13-15-32(16-14-31)27-24-7-6-23(28)18-22(24)5-4-21-3-2-10-29-26(21)27/h2-3,6-7,10,18,20,27H,4-5,8-9,11-17H2,1H3/t27-/m0/s1
InChIKey
JXNIGCDETYLKAE-MHZLTWQESA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.