Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX4V8M
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| Drug Name |
1-(4-Methoxyphenyl)-6,7-methylenedioxy-2-(4-methylthiophenyl-ureido)-2H-isoquinolin-3-one
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| Synonyms |
CHEMBL596265
|
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C25H21N3O5S
|
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| Canonical SMILES |
COc1ccc(cc1)C2=C3C=C4OCOC4=CC3=CC(=O)N2NC(=O)Nc5ccc(SC)cc5
|
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| InChI |
InChI=1S/C25H21N3O5S/c1-31-18-7-3-15(4-8-18)24-20-13-22-21(32-14-33-22)11-16(20)12-23(29)28(24)27-25(30)26-17-5-9-19(34-2)10-6-17/h3-13H,14H2,1-2H3,(H2,26,27,30)
|
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| InChIKey |
KDCNFQOPLAMXSF-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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