Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX5FVE
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| Drug Name |
6-(2,6-Dichloro-phenyl)-2-(4-hydroxy-phenylamino)-8-methyl-8H-pyrido[2,3-d]pyrimidin-7-one triethylamine oxide
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| Synonyms |
CHEMBL320339
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C26H27Cl2N5O3
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| Canonical SMILES |
CC[N+]([O-])(CC)CCOc1ccc(Nc2ncc3C=C(C(=O)N(C)c3n2)c4c(Cl)cccc4Cl)cc1
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| InChI |
InChI=1S/C26H27Cl2N5O3/c1-4-33(35,5-2)13-14-36-19-11-9-18(10-12-19)30-26-29-16-17-15-20(25(34)32(3)24(17)31-26)23-21(27)7-6-8-22(23)28/h6-12,15-16H,4-5,13-14H2,1-3H3,(H,29,30,31)
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| InChIKey |
DLGVUWDAFXDBEG-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Basic fibroblast growth factor receptor 1 | Target Info | [1587926] | ||
| Platelet-derived growth factor receptor | Target Info | [1587926] | |||
| KEGG Pathway | MAPK signaling pathway | ||||
| Ras signaling pathway | |||||
| Rap1 signaling pathway | |||||
| PI3K-Akt signaling pathway | |||||
| Adherens junction | |||||
| Signaling pathways regulating pluripotency of stem cells | |||||
| Regulation of actin cytoskeleton | |||||
| Pathways in cancer | |||||
| Proteoglycans in cancer | |||||
| Prostate cancer | |||||
| Melanoma | |||||
| Central carbon metabolism in cancer | |||||
| NetPath Pathway | TCR Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| FGF signaling pathway | |||||
| Pathway Interaction Database | Glypican 1 network | ||||
| Syndecan-4-mediated signaling events | |||||
| N-cadherin signaling events | |||||
| FGF signaling pathway | |||||
| References | |||||
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