Drug Information

Drug General Information
Drug ID
DX6OXQ
Drug Name
8-Cyclopropylmethyl-3-(4-iodo-phenyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester
Synonyms
CHEMBL150084
Indication Discovery agent Investigative [1587926]
Formula
C19H24INO2
Canonical SMILES
COC(=O)C1C2CCC(CC1c3ccc(I)cc3)N2CC4CC4
InChI
InChI=1S/C19H24INO2/c1-23-19(22)18-16(13-4-6-14(20)7-5-13)10-15-8-9-17(18)21(15)11-12-2-3-12/h4-7,12,15-18H,2-3,8-11H2,1H3
InChIKey
ZGFXSRVXZARDSQ-UHFFFAOYSA-N
Target and Pathway
Target(s) Sodium-dependent noradrenaline transporter Target Info [1587926]
Sodium-dependent serotonin transporter Target Info [1587926]
KEGG Pathway Serotonergic synapse
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Adrenaline and noradrenaline biosynthesisP04373:5HT1 type receptor mediated signaling pathway
5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathway
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways Monoamine Transport
NRF2 pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsWP727:Monoamine Transport
SIDS Susceptibility Pathways
Synaptic Vesicle Pathway
Serotonin Transporter Activity
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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