Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX6PRB
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| Drug Name |
3-amino-N-(furan-2-ylmethyl)-5-oxo-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide
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| Synonyms |
CHEMBL1431996
|
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C17H15N3O3S
|
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| Canonical SMILES |
Nc1c(sc2nc3CCCC(=O)c3cc12)C(=O)NCc4occc4
|
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| InChI |
InChI=1S/C17H15N3O3S/c18-14-11-7-10-12(4-1-5-13(10)21)20-17(11)24-15(14)16(22)19-8-9-3-2-6-23-9/h2-3,6-7H,1,4-5,8,18H2,(H,19,22)
|
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| InChIKey |
IRDVCTIKJACDIY-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Estrogen receptor beta | Target Info | [1587926] | ||
| Induced myeloid leukemia cell differentiation protein Mcl-1 | Target Info | [1587926] | |||
| NetPath Pathway | TCR Signaling Pathway | ||||
| PANTHER Pathway | Apoptosis signaling pathway | ||||
| CCKR signaling map ST | |||||
| Pathway Interaction Database | Plasma membrane estrogen receptor signaling | ||||
| Validated nuclear estrogen receptor beta network | |||||
| Validated nuclear estrogen receptor alpha networke2f_pathway:E2F transcription factor network | |||||
| Direct p53 effectors | |||||
| IL6-mediated signaling events | |||||
| HIF-1-alpha transcription factor network | |||||
| WikiPathways | SIDS Susceptibility Pathways | ||||
| Ovarian Infertility Genes | |||||
| Integrated Pancreatic Cancer Pathway | |||||
| Nuclear ReceptorsWP254:Apoptosis | |||||
| miR-targeted genes in muscle cell - TarBase | |||||
| miR-targeted genes in lymphocytes - TarBase | |||||
| miR-targeted genes in leukocytes - TarBase | |||||
| Apoptosis Modulation and Signaling | |||||
| References | |||||
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