Drug Information

Drug General Information
Drug ID
DX7MGD
Drug Name
2-(Hexadecane-1-sulfonyl)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid hydroxyamide
Synonyms
CHEMBL435820
Indication Discovery agent Investigative [1587926]
Formula
C26H44N2O4S
Canonical SMILES
CCCCCCCCCCCCCCCCS(=O)(=O)N1Cc2ccccc2CC1C(=O)NO
InChI
InChI=1S/C26H44N2O4S/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17-20-33(31,32)28-22-24-19-16-15-18-23(24)21-25(28)26(29)27-30/h15-16,18-19,25,30H,2-14,17,20-22H2,1H3,(H,27,29)
InChIKey
ICZVHRMXNBNXEY-UHFFFAOYSA-N
Target and Pathway
Target(s) Stromelysin-1 Target Info [1587926]
Neutrophil collagenase Target Info [1587926]
KEGG Pathway TNF signaling pathway
Transcriptional misregulation in cancer
Rheumatoid arthritis
NetPath Pathway IL1 Signaling Pathway
IL4 Signaling Pathway
PANTHER Pathway Plasminogen activating cascade
CCKR signaling map STP00004:Alzheimer disease-presenilin pathway
Pathway Interaction Database Posttranslational regulation of adherens junction stability and dissassembly
p75(NTR)-mediated signaling
Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
Reactome Collagen degradation
Degradation of the extracellular matrix
Activation of Matrix Metalloproteinases
Assembly of collagen fibrils and other multimeric structures
EGFR Transactivation by GastrinR-HSA-1442490:Collagen degradation
WikiPathways Activation of Matrix Metalloproteinases
Gastrin-CREB signalling pathway via PKC and MAPK
Oncostatin M Signaling Pathway
Matrix MetalloproteinasesWP2769:Activation of Matrix Metalloproteinases
Matrix Metalloproteinases
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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