Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX7UWB
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| Drug Name |
(S)-4,4-dichloro-N-((S)-1-cyano-2-phenylethyl)-2-((S)-2,2,2-trifluoro-1-(4'-(methylsulfonyl)biphenyl-4-yl)ethylamino)butanamide
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| Synonyms |
CHEMBL1290084
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C28H26Cl2F3N3O3S
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| Canonical SMILES |
CS(=O)(=O)c1ccc(cc1)c2ccc(cc2)[C@H](N[C@@H](CC(Cl)Cl)C(=O)N[C@@H](Cc3ccccc3)C#N)C(F)(F)F
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| InChI |
InChI=1S/C28H26Cl2F3N3O3S/c1-40(38,39)23-13-11-20(12-14-23)19-7-9-21(10-8-19)26(28(31,32)33)36-24(16-25(29)30)27(37)35-22(17-34)15-18-5-3-2-4-6-18/h2-14,22,24-26,36H,15-16H2,1H3,(H,35,37)/t22-,24-,26-/m0/s1
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| InChIKey |
UULSCOLFHVNVPK-GVUKDKGQSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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