Drug Information

Drug General Information
Drug ID
DX8LFA
Drug Name
4-(5-{[3-(3,5-Dichloro-phenyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[d]azepin-1-ylamino]-methyl}-imidazol-1-ylmethyl)-benzonitrile
Synonyms
CHEMBL165068
Indication Discovery agent Investigative [1587926]
Formula
C28H23Cl2N5O
Canonical SMILES
Clc1cc(Cl)cc(c1)N2CCc3ccccc3C(NCc4cncn4Cc5ccc(cc5)C#N)C2=O
InChI
InChI=1S/C28H23Cl2N5O/c29-22-11-23(30)13-24(12-22)35-10-9-21-3-1-2-4-26(21)27(28(35)36)33-16-25-15-32-18-34(25)17-20-7-5-19(14-31)6-8-20/h1-8,11-13,15,18,27,33H,9-10,16-17H2
InChIKey
ONWQFUUORXWXJQ-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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