Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX8NVM
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| Drug Name |
N-(1-((cyanomethyl)carbamoyl)cyclohexyl)-4-(2-(4-(2-methoxyethyl)piperazin-1-yl)thiazol-4-yl)benzamide
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| Synonyms |
CHEMBL200602
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C26H34N6O3S
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| Canonical SMILES |
COCCN1CCN(CC1)c2nc(cs2)c3ccc(cc3)C(=O)NC4(CCCCC4)C(=O)NCC#N
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| InChI |
InChI=1S/C26H34N6O3S/c1-35-18-17-31-13-15-32(16-14-31)25-29-22(19-36-25)20-5-7-21(8-6-20)23(33)30-26(9-3-2-4-10-26)24(34)28-12-11-27/h5-8,19H,2-4,9-10,12-18H2,1H3,(H,28,34)(H,30,33)
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| InChIKey |
AVWYVNDORFCKIL-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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