Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX8QP9
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| Drug Name |
N4-(3-bromophenyl)-6-(2-chlorobenzyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
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| Synonyms |
CHEMBL499345
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C19H15BrClN5
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| Canonical SMILES |
Nc1nc(Nc2cccc(Br)c2)c3cc(Cc4ccccc4Cl)[nH]c3n1
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| InChI |
InChI=1S/C19H15BrClN5/c20-12-5-3-6-13(9-12)23-17-15-10-14(24-18(15)26-19(22)25-17)8-11-4-1-2-7-16(11)21/h1-7,9-10H,8H2,(H4,22,23,24,25,26)
|
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| InChIKey |
ISXTVMIMVFTRIL-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Epidermal growth factor receptor III | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathway | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY network | |||||
| References | |||||
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