Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX9TEO
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| Drug Name |
(S)-4-Methyl-2-(4''-piperazin-1-yl-biphenyl-4-ylamino)-pentanoic acid cyanomethyl-amide
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| Synonyms |
CHEMBL184859
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C24H31N5O
|
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| Canonical SMILES |
CC(C)C[C@H](Nc1ccc(cc1)c2ccc(cc2)N3CCNCC3)C(=O)NCC#N
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| InChI |
InChI=1S/C24H31N5O/c1-18(2)17-23(24(30)27-12-11-25)28-21-7-3-19(4-8-21)20-5-9-22(10-6-20)29-15-13-26-14-16-29/h3-10,18,23,26,28H,12-17H2,1-2H3,(H,27,30)/t23-/m0/s1
|
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| InChIKey |
DNRVBUZMGUEKCJ-QHCPKHFHSA-N
|
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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