Drug Information

Drug General Information
Drug ID
DX9WJ6
Drug Name
1-(4'-Aminophenyl)-6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-sulfonamide
Synonyms
CHEMBL469148
Indication Discovery agent Investigative [1587926]
Formula
C17H21N3O4S
Canonical SMILES
COc1cc2CCN(C(c3ccc(N)cc3)c2cc1OC)S(=O)(=O)N
InChI
InChI=1S/C17H21N3O4S/c1-23-15-9-12-7-8-20(25(19,21)22)17(14(12)10-16(15)24-2)11-3-5-13(18)6-4-11/h3-6,9-10,17H,7-8,18H2,1-2H3,(H2,19,21,22)
InChIKey
LRJPUNGMUDNTMG-UHFFFAOYSA-N
Target and Pathway
Target(s) Carbonic anhydrase I Target Info [1587926]
Carbonic anhydrase IX Target Info [1587926]
KEGG Pathway Nitrogen metabolismhsa00910:Nitrogen metabolism
Pathway Interaction Database C-MYB transcription factor networkhif1_tfpathway:HIF-1-alpha transcription factor network
PathWhiz Pathway Gastric Acid Production
Reactome Erythrocytes take up carbon dioxide and release oxygen
Erythrocytes take up oxygen and release carbon dioxide
Reversible hydration of carbon dioxideR-HSA-1234158:Regulation of gene expression by Hypoxia-inducible Factor
Reversible hydration of carbon dioxide
WikiPathways Reversible Hydration of Carbon Dioxide
Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes
Uptake of Oxygen and Release of Carbon Dioxide by ErythrocytesWP2877:Vitamin D Receptor Pathway
Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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