Drug Information
| Drug General Information | |||||
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| Drug ID |
DX9WR5
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| Drug Name |
(S)-3-tert-butyl-N-(1-(cyanomethylamino)-3-(3-(5-(hydroxymethyl)-1,3,4-oxadiazol-2-yl)phenyl)-1-oxopropan-2-yl)-1-methyl-1H-pyrazole-5-carboxamide
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| Synonyms |
CHEMBL549791
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C23H27N7O4
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| Canonical SMILES |
Cn1nc(cc1C(=O)N[C@@H](Cc2cccc(c2)c3oc(CO)nn3)C(=O)NCC#N)C(C)(C)C
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| InChI |
InChI=1S/C23H27N7O4/c1-23(2,3)18-12-17(30(4)29-18)21(33)26-16(20(32)25-9-8-24)11-14-6-5-7-15(10-14)22-28-27-19(13-31)34-22/h5-7,10,12,16,31H,9,11,13H2,1-4H3,(H,25,32)(H,26,33)/t16-/m0/s1
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| InChIKey |
ZZDKLZGEJYCCFB-INIZCTEOSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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