Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXDR0F
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| Drug Name |
(7,8-dimethoxy-10,11-dihydro-5H-2,4,5,11-tetraaza-dibenzo[a,d]cyclohepten-1-yl)-((R)-1-phenyl-ethyl)-amine
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| Synonyms |
CHEMBL379001
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C21H23N5O2
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| Canonical SMILES |
COc1cc2CNc3c(N[C@H](C)c4ccccc4)ncnc3Nc2cc1OC
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| InChI |
InChI=1S/C21H23N5O2/c1-13(14-7-5-4-6-8-14)25-20-19-21(24-12-23-20)26-16-10-18(28-3)17(27-2)9-15(16)11-22-19/h4-10,12-13,22H,11H2,1-3H3,(H2,23,24,25,26)/t13-/m1/s1
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| InChIKey |
LPWLEMJTQPNOMS-CYBMUJFWSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Epidermal growth factor receptor III | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathway | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY network | |||||
| References | |||||
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