Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXGC6U
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| Drug Name |
(S)-N-((S)-1-cyano-2-phenylethyl)-3-cyclopropyl-2-((S)-2,2,2-trifluoro-1-(4'-(methylsulfonyl)biphenyl-4-yl)ethylamino)propanamide
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| Synonyms |
CHEMBL1289988
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C30H30F3N3O3S
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| Canonical SMILES |
CS(=O)(=O)c1ccc(cc1)c2ccc(cc2)[C@H](N[C@@H](CC3CC3)C(=O)N[C@@H](Cc4ccccc4)C#N)C(F)(F)F
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| InChI |
InChI=1S/C30H30F3N3O3S/c1-40(38,39)26-15-13-23(14-16-26)22-9-11-24(12-10-22)28(30(31,32)33)36-27(18-21-7-8-21)29(37)35-25(19-34)17-20-5-3-2-4-6-20/h2-6,9-16,21,25,27-28,36H,7-8,17-18H2,1H3,(H,35,37)/t25-,27-,28-/m0/s1
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| InChIKey |
JNRFQDUMCHRUFL-MYKRZTLLSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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