Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXIR5N
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| Drug Name |
N-(1-((cyanomethyl)carbamoyl)cyclohexyl)-4-(4-methylpiperazin-1-yl)benzamide
|
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| Synonyms |
CHEMBL440035
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C21H29N5O2
|
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| Canonical SMILES |
CN1CCN(CC1)c2ccc(cc2)C(=O)NC3(CCCCC3)C(=O)NCC#N
|
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| InChI |
InChI=1S/C21H29N5O2/c1-25-13-15-26(16-14-25)18-7-5-17(6-8-18)19(27)24-21(9-3-2-4-10-21)20(28)23-12-11-22/h5-8H,2-4,9-10,12-16H2,1H3,(H,23,28)(H,24,27)
|
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| InChIKey |
MLCJLRMXTIAXRI-UHFFFAOYSA-N
|
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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