TTD | Drug: DXLJ1P

Drug General Information
Drug ID	DXLJ1P
Drug Name	7-(3-(4-fluoropiperidin-1-yl)propoxy)-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline
Synonyms	CHEMBL397065
Indication	Discovery agent		Investigative	[1587926]
Formula	C24H31FN2O
Canonical SMILES	CN1CC(c2ccccc2)c3ccc(OCCCN4CCC(F)CC4)cc3C1
InChI	InChI=1S/C24H31FN2O/c1-26-17-20-16-22(28-15-5-12-27-13-10-21(25)11-14-27)8-9-23(20)24(18-26)19-6-3-2-4-7-19/h2-4,6-9,16,21,24H,5,10-15,17-18H2,1H3
InChIKey	RELMLKVZHCPAMI-UHFFFAOYSA-N
Target and Pathway
Target(s)	Histamine H3 receptor	Target Info		[1587926]
Target(s)	Sodium-dependent serotonin transporter	Target Info		[1587926]
KEGG Pathway	Neuroactive ligand-receptor interactionhsa04726:Serotonergic synapse
NetPath Pathway	TCR Signaling Pathway
PANTHER Pathway	5HT1 type receptor mediated signaling pathway
	5HT2 type receptor mediated signaling pathway
	5HT3 type receptor mediated signaling pathway
	5HT4 type receptor mediated signaling pathway
Reactome	Histamine receptors
Reactome	G alpha (i) signalling events
WikiPathways	Monoamine Transport
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signalingWP727:Monoamine Transport
	SIDS Susceptibility Pathways
	NRF2 pathway
	Synaptic Vesicle Pathway
	Serotonin Transporter Activity
References
Ref 1587926	URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926	URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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Drug Information