Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXRR2O
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| Drug Name |
SID29216691
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| Synonyms |
CHEMBL1574144
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C28H29F3N4O6
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| Canonical SMILES |
COc1ccc(CCN2C(=O)NC(=O)C3=C2NC(=O)C3(NC(=O)c4ccc(cc4)C(C)(C)C)C(F)(F)F)cc1OC
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| InChI |
InChI=1S/C28H29F3N4O6/c1-26(2,3)17-9-7-16(8-10-17)22(36)34-27(28(29,30)31)20-21(32-24(27)38)35(25(39)33-23(20)37)13-12-15-6-11-18(40-4)19(14-15)41-5/h6-11,14H,12-13H2,1-5H3,(H,32,38)(H,34,36)(H,33,37,39)
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| InChIKey |
KKZXPKNNWWLGJN-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Estrogen receptor beta | Target Info | [1587926] | ||
| mRNA of androgen receptor | Target Info | [1587926] | |||
| Pathway Interaction Database | Plasma membrane estrogen receptor signaling | ||||
| Validated nuclear estrogen receptor beta network | |||||
| Validated nuclear estrogen receptor alpha networksmad2_3nuclearpathway:Regulation of nuclear SMAD2/3 signaling | |||||
| Coregulation of Androgen receptor activity | |||||
| Regulation of Androgen receptor activity | |||||
| Nongenotropic Androgen signaling | |||||
| Regulation of nuclear beta catenin signaling and target gene transcription | |||||
| FOXA1 transcription factor network | |||||
| Notch-mediated HES/HEY network | |||||
| References | |||||
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