Drug Information

Drug General Information
Drug ID
DXS1HY
Drug Name
4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-(4-oxo-pentanoyl)-piperazine-2-carboxylic acid (pyridin-3-ylmethyl)-amide
Synonyms
CHEMBL427191
Indication Discovery agent Investigative [1587926]
Formula
C30H31BrClN5O3
Canonical SMILES
CC(=O)CCC(=O)N1CCN(CC1C(=O)NCc2cccnc2)C3c4ccc(Cl)cc4CCc5cc(Br)cnc35
InChI
InChI=1S/C30H31BrClN5O3/c1-19(38)4-9-27(39)37-12-11-36(18-26(37)30(40)35-16-20-3-2-10-33-15-20)29-25-8-7-24(32)14-21(25)5-6-22-13-23(31)17-34-28(22)29/h2-3,7-8,10,13-15,17,26,29H,4-6,9,11-12,16,18H2,1H3,(H,35,40)
InChIKey
ZARKMBOXAZGLSX-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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