Drug Information

Drug General Information
Drug ID
DXT9X3
Drug Name
N-benzyl-N-methyl-5-(2,2,2-trifluoroacetyl)thiophene-2-sulfonamide
Synonyms
CHEMBL494813
Indication Discovery agent Investigative [1587926]
Formula
C14H12F3NO3S2
Canonical SMILES
CN(Cc1ccccc1)S(=O)(=O)c2ccc(s2)C(=O)C(F)(F)F
InChI
InChI=1S/C14H12F3NO3S2/c1-18(9-10-5-3-2-4-6-10)23(20,21)12-8-7-11(22-12)13(19)14(15,16)17/h2-8H,9H2,1H3
InChIKey
QMDPGLMZJJTIKT-UHFFFAOYSA-N
Target and Pathway
Target(s) Histone deacetylase 6 Target Info [1587926]
Histone deacetylase 4 Target Info [1587926]
KEGG Pathway Alcoholism
Viral carcinogenesishsa05034:Alcoholism
Epstein-Barr virus infection
Viral carcinogenesis
MicroRNAs in cancer
NetPath Pathway IL2 Signaling Pathway
Pathway Interaction Database Signaling events mediated by HDAC Class II
Signaling events mediated by HDAC Class Ihdac_classii_pathway:Signaling events mediated by HDAC Class II
Signaling events mediated by HDAC Class III
Signaling events mediated by HDAC Class I
Sumoylation by RanBP2 regulates transcriptional repression
Validated nuclear estrogen receptor alpha network
Reactome NOTCH1 Intracellular Domain Regulates Transcription
Constitutive Signaling by NOTCH1 PEST Domain Mutants
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
Assembly of the primary ciliumR-HSA-2122947:NOTCH1 Intracellular Domain Regulates Transcription
WikiPathways Ectoderm Differentiation
Neural Crest Differentiation
Cell CycleWP474:Endochondral Ossification
Cardiac Hypertrophic Response
miR-targeted genes in muscle cell - TarBase
miR-targeted genes in lymphocytes - TarBase
miR-targeted genes in epithelium - TarBase
TarBasePathway
Cell Cycle
MicroRNAs in cardiomyocyte hypertrophy
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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