Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXU9BQ
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| Drug Name |
3-[(R)-2-Cyano-2-((S)-3-phenyl-2-phenylamino-propionylamino)-ethoxymethyl]-benzoic acid
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| Synonyms |
CHEMBL335269
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C26H25N3O4
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| Canonical SMILES |
OC(=O)c1cccc(COC[C@H](NC(=O)[C@H](Cc2ccccc2)Nc3ccccc3)C#N)c1
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| InChI |
InChI=1S/C26H25N3O4/c27-16-23(18-33-17-20-10-7-11-21(14-20)26(31)32)29-25(30)24(15-19-8-3-1-4-9-19)28-22-12-5-2-6-13-22/h1-14,23-24,28H,15,17-18H2,(H,29,30)(H,31,32)/t23-,24+/m1/s1
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| InChIKey |
MCJNEOXSKWPBMT-RPWUZVMVSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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