Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXW1OO
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| Drug Name |
(2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-[(quinolin-8-ylmethyl)-amino]-succinamide
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| Synonyms |
CHEMBL439983
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C25H37N5O4
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| Canonical SMILES |
CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NCc1cccc2cccnc12)C(=O)NO)C(C)(C)C
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| InChI |
InChI=1S/C25H37N5O4/c1-15(2)13-18(22(31)29-21(24(33)26-6)25(3,4)5)20(23(32)30-34)28-14-17-10-7-9-16-11-8-12-27-19(16)17/h7-12,15,18,20-21,28,34H,13-14H2,1-6H3,(H,26,33)(H,29,31)(H,30,32)/t18-,20+,21-/m1/s1
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| InChIKey |
DJQJEICJRBFEOV-HLAWJBBLSA-N
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| Target and Pathway | |||||
| Target(s) | Interstitial collagenase | Target Info | [1587926] | ||
| Neutrophil collagenase | Target Info | [1587926] | |||
| WikiPathways | TGF beta Signaling Pathway | ||||
| Bladder Cancer | |||||
| Activation of Matrix Metalloproteinases | |||||
| Degradation of collagen | |||||
| Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis | |||||
| Oncostatin M Signaling Pathway | |||||
| Prostate Cancer | |||||
| Integrated Breast Cancer Pathway | |||||
| Integrated Cancer pathway | |||||
| Cell surface interactions at the vascular wall | |||||
| Matrix MetalloproteinasesWP2769:Activation of Matrix Metalloproteinases | |||||
| Matrix Metalloproteinases | |||||
| References | |||||
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