Drug Information

Drug General Information
Drug ID
DXXU6A
Drug Name
1-[4-(3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-(1-oxy-pyridin-3-yl)-ethanone
Synonyms
CHEMBL171463
Indication Discovery agent Investigative [1587926]
Formula
C25H24BrClN4O2
Canonical SMILES
[O-][n+]1cccc(CC(=O)N2CCN(CC2)C3c4ccc(Cl)cc4CCc5cc(Br)cnc35)c1
InChI
InChI=1S/C25H24BrClN4O2/c26-20-13-19-4-3-18-14-21(27)5-6-22(18)25(24(19)28-15-20)30-10-8-29(9-11-30)23(32)12-17-2-1-7-31(33)16-17/h1-2,5-7,13-16,25H,3-4,8-12H2
InChIKey
OXRPHVZDZIHKNJ-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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