Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXZD7U
|
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| Drug Name |
5-(5,6-Dimethyl-pyrrolo[2,1-f][1,2,4]triazin-4-ylamino)-2-methyl-phenol
|
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| Synonyms |
CHEMBL186001
|
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C15H16N4O
|
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| Canonical SMILES |
Cc1ccc(Nc2ncnn3cc(C)c(C)c23)cc1O
|
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| InChI |
InChI=1S/C15H16N4O/c1-9-4-5-12(6-13(9)20)18-15-14-11(3)10(2)7-19(14)17-8-16-15/h4-8,20H,1-3H3,(H,16,17,18)
|
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| InChIKey |
NSSREJILCYZENK-UHFFFAOYSA-N
|
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Epidermal growth factor receptor III | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathway | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY network | |||||
| References | |||||
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