Drug Information

Drug General Information
Drug ID
D00FBC
Former ID
DIB007890
Drug Name
KHK-6188
Indication Neuropathic pain [ICD9: 356.0, 356.8; ICD10:G64, G90.0] Phase 2 [523813]
Company
Kyowa Hakko Kirin Co Ltd
Target and Pathway
Target(s) Cannabinoid receptor 2 Target Info Agonist [551579]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 523813ClinicalTrials.gov (NCT01544296) A Comparative Study of KHK6188. U.S. National Institutes of Health.
Ref 551579Recent Development of CB2 Selective and Peripheral CB1/CB2 Cannabinoid Receptor Ligands. Current Medicinal Chemistry . 10/2013; 21(2).

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