Drug Information
Drug General Information | |||||
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Drug ID |
D00KVE
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Former ID |
DIB000567
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Drug Name |
Cutamesine
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Synonyms |
AGY-94806; Msc-1; SA-4502; SA-4503; Sigma opioid receptor agonist, Santen
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Drug Type |
Small molecular drug
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Indication | Major depressive disorder [ICD9: 296.2, 296.3, 710.0; ICD10:F32, F33, M32] | Preclinical | [546327] | ||
Company |
Santen Pharmaceutical Co Ltd
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Structure |
Download2D MOL |
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Formula |
C23H32N2O2
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Canonical SMILES |
N1(CCc2cc(c(cc2)OC)OC)CCN(CC1)CCCc1ccccc1
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Sigma(1)-type opioid receptor | Target Info | Agonist | [526642], [532713], [534601] | |
References | |||||
Ref 526642 | Dextromethorphan antagonizes the acute depletion of brain serotonin by p-chloroamphetamine and H75/12 in rats. Brain Res. 1992 Oct 30;594(2):323-6. | ||||
Ref 532713 | Antitussives and substance abuse. Subst Abuse Rehabil. 2013 Nov 6;4:75-82. | ||||
Ref 534601 | Effect of SA4503, a novel sigma1 receptor agonist, against glutamate neurotoxicity in cultured rat retinal neurons. Eur J Pharmacol. 1998 Jan 19;342(1):105-11. |
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