Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D00UVA
|
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| Former ID |
DNAP001267
|
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| Drug Name |
Carfilzomib
|
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| Drug Type |
Small molecular drug
|
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| Company |
Onyx Pharmaceuticals
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C40H57N5O7
|
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| InChI |
InChI=1S/C40H57N5O7/c1-27(2)22-32(36(47)40(5)26-52-40)42-39(50)34(24-30-14-10-7-11-15-30)44-38(49)33(23-28(3)4)43-37(48)31(17-16-29-12-8-6-9-13-29)41-35(46)25-45-18-20-51-21-19-45/h6-15,27-28,31-34H,16-26H2,1-5H3,(H,41,46)(H,42,50)(H,43,48)(H,44,49)/t31-,32-,33-,34-,40+/m0/s1
|
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| InChIKey |
BLMPQMFVWMYDKT-NZTKNTHTSA-N
|
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| CAS Number |
CAS 868540-17-4
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
16658822, 16812122, 23677375, 42698607, 79448448, 92309411, 96025563, 103652542, 104120353, 124360326, 124955654, 126666807, 135195928, 137232018, 139716850, 144206630, 152159713, 160644888, 162012022, 162220763, 163423918, 163620703, 163686020, 164041848, 170466878, 172918803, 174006371, 174531085, 175266683, 175427135, 178103992, 186014508, 189158922, 198993058, 223377621, 223683622, 223704692, 224740444, 226463473, 242082461, 248344031, 249814475, 251970960, 252451821, 252553657
|
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| ChEBI ID |
ChEBI:65347
|
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| SuperDrug ATC ID |
L01XX45
|
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| Target and Pathway | |||||
| Target(s) | Proteasome | Target Info | Modulator | [532210] | |
| References | |||||
| Ref 532210 | Nat Rev Drug Discov. 2013 Feb;12(2):87-90. | ||||
| Ref 542445 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7420). | ||||
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