Drug Information

Drug General Information
Drug ID
D01APA
Former ID
DIB019342
Drug Name
compound 20o
Drug Type
Small molecular drug
Indication Discovery agent Investigative [532047], [541199]
Structure
Download
2D MOL
Formula
C32H43N7O7
InChI
InChI=1S/C32H43N7O7/c1-2-3-19-45-32(44)37-17-15-36(16-18-37)27(40)21-33-30(42)25-20-29(39(35-25)24-11-5-4-6-12-24)46-22-28(41)38-14-8-13-26(38)31(43)34-23-9-7-10-23/h4-6,11-12,20,23,26H,2-3,7-10,13-19,21-22H2,1H3,(H,33,42)(H,34,43)/t26-/m0/s1
InChIKey
QCKRRHRHLONWIP-SANMLTNESA-N
PubChem Compound ID
66855377
PubChem Substance ID
163328005, 163346167, 163455017, 178102529, 227213800, 247296824
Target and Pathway
Target(s) P2Y purinoceptor 12 Target Info Antagonist [532047]
KEGG Pathway Platelet activation
Reactome P2Y receptors
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Signal amplification
GPCR ligand binding
GPCR downstream signaling
References
Ref 532047Identification of high-affinity P2Y??? antagonists based on a phenylpyrazole glutamic acid piperazine backbone. J Med Chem. 2012 Oct 25;55(20):8615-29.
Ref 541199(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5906).
Ref 532047Identification of high-affinity P2Y??? antagonists based on a phenylpyrazole glutamic acid piperazine backbone. J Med Chem. 2012 Oct 25;55(20):8615-29.

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