Drug Information

Drug General Information
Drug ID
D01KIS
Former ID
DIB015387
Drug Name
CGP-53437
Synonyms
CGP-58707
Drug Type
Small molecular drug
Indication Human immunodeficiency virus infection [ICD9: 279.3; ICD10:B20-B26] Discontinued in Phase 1 [545200]
Company
Novartis AG
Structure
Download
2D MOL

3D MOL
Formula
C42H56N4O7
Canonical SMILES
C(=O)(N[C@H](C(=O)N1CCOCC1)Cc1ccccc1)[C@@H](NC(=O)[C@@H<br />](C[C@@H]([C@@H](NC(=O)OC(C)(C)C)Cc1ccccc1)O)Cc1ccccc1)<br />C(C)C
CAS Number
CAS 150736-68-8
PubChem Compound ID
5480679
Target and Pathway
Target(s) HIV protease Target Info Inhibitor [533961]
References
Ref 545200Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002438)
Ref 533961CGP 53437, an orally bioavailable inhibitor of human immunodeficiency virus type 1 protease with potent antiviral activity. Antimicrob Agents Chemother. 1993 Oct;37(10):2087-92.

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