Drug General Information
Drug ID
D01MAU
Former ID
DIB013153
Drug Name
AZD-1446
Synonyms
TC-6683; Alpha-4 beta-2 neuronal nicotinic receptor modulator (oral, cognitive disorder), Targacept/AstraZeneca
Drug Type
Small molecular drug
Indication Alzheimer disease [ICD9: 331; ICD10:G30] Phase 2 [522853]
Company
Targacept Inc
Structure
Download
2D MOL

3D MOL

Formula
C11H13ClN2O2
Canonical SMILES
Clc1oc(cc1)C(=O)N2CC3CNCC3C2
InChI
1S/C11H13ClN2O2/c12-10-2-1-9(16-10)11(15)14-5-7-3-13-4-8(7)6-14/h1-2,7-8,13H,3-6H2
InChIKey
GTUIQNHJSXQMKW-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) Nicotinic ACh receptor alpha 4/beta 2 Target Info Modulator
References
Ref 522853ClinicalTrials.gov (NCT01012375) Study to Investigate the Efficacy and Tolerability of AZD1446 in Adult ADHD Patients.. U.S. National Institutes of Health.

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