Drug General Information
Drug ID
D01PJR
Former ID
DAP000517
Drug Name
Tocainide
Synonyms
Taquidil; Tocainida; Tocainidum; Tonocard; Astra W 36095; Tocainida [INN-Spanish]; Tocainidum [INN-Latin]; W-36095; Tocainide (USAN/INN); Tocainide [USAN:BAN:INN]; Alanyl-2,6-xylidide; N-(2,6-dimethylphenyl)alaninamide; (-)-2-Amino-N-(2,6-dimethylphenyl)propanamide; 2-AMINO-N-(2,6-DIMETHYLPHENYL)PROPANAMIDE; 2-Amino-2',6'-propionoxylidide; 2-Amino-N-(2,6-dimethylphenyl)propionamid
Drug Type
Small molecular drug
Indication Ventricular arrhythmias [ICD9: 427.1; ICD10:I47.2] Approved [538501], [542331]
Therapeutic Class
Antiarrhythmic Agents
Structure
Download
2D MOL

3D MOL

Formula
C11H16N2O
InChI
InChI=1S/C11H16N2O/c1-7-5-4-6-8(2)10(7)13-11(14)9(3)12/h4-6,9H,12H2,1-3H3,(H,13,14)
InChIKey
BUJAGSGYPOAWEI-UHFFFAOYSA-N
CAS Number
CAS 41708-72-9
PubChem Compound ID
PubChem Substance ID
SuperDrug ATC ID
C01BB03
SuperDrug CAS ID
cas=041708729
Target and Pathway
Target(s) E3 ubiquitin protein ligase COP1 Target Info Modulator [556264]
KEGG Pathway p53 signaling pathway
Ubiquitin mediated proteolysis
PANTHER Pathway P53 pathway feedback loops 1
Pathway Interaction Database ATM pathway
Direct p53 effectors
p53 pathway
References
Ref 538501FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 018257.
Ref 542331(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7309).
Ref 556264Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

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