Drug General Information
Drug ID
D01TFQ
Former ID
DNC009310
Drug Name
KNI-10124
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529771]
Structure
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2D MOL

3D MOL

Formula
C34H39N3O7S
Canonical SMILES
CC1(C(N(CS1)C(=O)C(C(CC2=CC=CC=C2)NC(=O)COC3=CC=CC(=C3)<br />CO)O)C(=O)NC4C(CC5=CC=CC=C45)O)C
InChI
1S/C34H39N3O7S/c1-34(2)31(32(42)36-29-25-14-7-6-12-23(25)17-27(29)39)37(20-45-34)33(43)30(41)26(16-21-9-4-3-5-10-21)35-28(40)19-44-24-13-8-11-22(15-24)18-38/h3-15,26-27,29-31,38-39,41H,16-20H2,1-2H3,(H,35,40)(H,36,42)/t26-,27+,29-,30-,31+/m0/s1
InChIKey
NRLFBLHYKZDHHW-VFCPCCRCSA-N
PubChem Compound ID
Target and Pathway
Target(s) Plasmepsin 2 Target Info Inhibitor [529771]
References
Ref 529771Bioorg Med Chem. 2008 Dec 1;16(23):10049-60. Epub 2008 Oct 10.Antimalarial activity enhancement in hydroxymethylcarbonyl (HMC) isostere-based dipeptidomimetics targeting malarial aspartic protease plasmepsin.
Ref 529771Bioorg Med Chem. 2008 Dec 1;16(23):10049-60. Epub 2008 Oct 10.Antimalarial activity enhancement in hydroxymethylcarbonyl (HMC) isostere-based dipeptidomimetics targeting malarial aspartic protease plasmepsin.

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